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Celebrex is a Cox-2 inhibitor originally approved for treatment of rheumatoid arthritis and osteoarthritis. The drug was later approved as a treatment aimed at reducing the number of intestinal polyps in patients with familial adenotamous polyposis. There are now concerns that Celebrex usage may increase the risk of heart attack or strokes in some people. The FDA has allowed Celebrex to remain on the market, but as of 4/7/05, the label must include a black box warning of the risk of cardiovascular and gastrointestinal risks.

Side Effects of Celebrex

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In the APC clinical trial, patients taking 400 mg. of Celebrex twice daily had a 3.4 times greater risk of cardiovascular events compared to placebo. For patients in the trial taking 200 mg. of Celebrex twice daily, the risk was 2.5 times greater. The average duration of treatment in the trial was 33 months. However, a similar ongoing study comparing Celebrex 400 mg. once a day versus placebo in patients followed for a similar period of time has not shown increased risk.

Pharmaceutical Litigation Attorneys at Bailey & Galyen have extensive experience in cases involving injury or wrongful death associated with prescription drugs. Contact us to set an appointment with an attorney to discuss your case.

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