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Dilantin– Yaz / Yazmin – ReglanHormone Replacement Therapy


Dilantin

Dilantin is an antiepileptic drug which can be useful in the treatment of epilepsy. It can cause very painful and disfiguring severe skin blistering known as Stevens-Johnson Syndrome and toxic epidermal necrolysis.

On 11/24/2008 , FDA announced it is investigating new preliminary data regarding a potential increased risk of serious skin reactions including Stevens Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) from phenytoin therapy. These reactions are estimated to occur in 1 to 6 per 10,000 users of Dilantin.

If you were prescribed and took DILANTIN prior to April, 2009, were diagnosed with Stevens Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) while taking DILANTIN, received medical attention for either Stevens Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN), call us to discuss your legal rights.


Yaz / Yazmin

YAZ / YASMIN is a birth control medication that can increase risk of strokes, heart attacks and blood clots.

Bayer, the manufacturer of the birth control pills Yaz and Yasmin, is alleged to have concealed health risks associated with these dangerous drugs, such as an increased risk of strokes, heart attacks and blood clots , and further, Bayer lied about their effectiveness.

Yaz and Yasmin are ”fourth generation” birth control pills which contain a new ingredient, drospirenone, and combine estrogen and progestin to prevent pregnancy.

Drospirenone, a diuretic, causes an increase in potassium which can lead to ”hyperkalemia” or unsafe levels of potassium that disrupt heart rhythms and slow the flow of blood, leading to clotting. Yaz/Yasmin was Bayer’s top-selling pharmaceuticals last year, with global sales of $1.8 billion.

In addition to the lawsuits, the drugs remain under scrutiny by the Food and Drug Administration about quality control issues at a company plant that makes drospirenone.

Bayer has been warned repeatedly about advertising for Yaz and Yasmin, from ads that overstated their safety to others that inaccurately touted effectiveness in treating acne and premenstrual syndrome.


Reglan

Reglan is a short-term (4 to 12 weeks) therapy for adults with symptomatic, documented gastroesophageal reflux who fail to respond to conventional therapy.

The FDA has required Reglan’s manufacturer to include a Black Box Warning in its label. A Black Box Warning is the strongest possible warning for prescription drugs. Pharmaceutical companies avoid Black Box Warnings because prescribing doctors avoid prescribing drugs with Black Box Warnings.

The Black Box Warning warns that Reglan can cause tardive dyskinesia, a serious movement disorder that is often irreversible and disfiguring disorder characterized by involuntary movements of the face, tongue, or extremities . The risk of developing tardive dyskinesia increases with duration of treatment and total cumulative dose. Less commonly, the syndrome can develop after relatively brief treatment periods at low doses; in these cases, symptoms appear more likely to be reversible. There is no known treatment for established cases of tardive dyskinesia although the syndrome may remit, partially or completely, within several weeks-to-months after metoclopramide is withdrawn.

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Hormone Replacement Therapy

Hormone replacement therapy (HRT) is medication that contains one or more female hormones, commonly estrogen plus progestin (synthetic progesterone). HRT is most often used to treat symptoms of menopause such as ”hot flashes,” vaginal dryness, mood swings, sleep disorders, and decreased sexual desire. This medication may be taken in the form of a pill, a patch, or vaginal cream. Some women receive estrogen-only therapy (usually women who have had their uterus removed). Based on early studies, many physicians used to believe that HRT might be beneficial for reducing the risk of heart disease and bone fractures caused by osteoporosis (thinning of the bones) in addition to treating menopausal symptoms. Prescription drugs commonly used for HRT are Premarin, Prempro, FemHrt Activella, Ortho-Prefest and Premphase. Both Premarin and Prempro have been linked to an increased risk of cancer, cardiovascular problems, asthma and immune system disorders such as lupus.

Read More About Hormone Replacement Therapy

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